“思壮”虫草菌丝体胶囊免疫功能评价

EVALUATION ON IMMUNITY FUNCTION OF "STRONG" CORDYCEPS MECYLIUM CAPSULES

将“思壮”虫草菌丝体胶囊（商品名）经口给予小鼠，在４５、４５０（相当于成人每日每公斤推荐摄入量的１０倍）和９００ｍｇ／ｋｇ体重剂量下，在１５～３０ｄ时，通过二硝基氟苯（ＤＮＦＢ）诱导小鼠迟发性变态反应（ＤＴＨ）、血清溶血素试验和小鼠碳廓清试验，表明中、高剂量“思壮”虫草菌丝体胶囊具有增强小鼠细胞免疫功能，而３种剂量均能明显增强小鼠体液免疫功能和单核巨噬细胞吞噬功能，且有剂量－反应关系，由此证明“思壮”虫草菌丝体胶囊有明显的免疫调节作用。

Mice were reared with mycelia from STRONG CORDYCEPS MYCELIUM CAPSULES (commercial name) at doses of 45, 450, and 900mg mycelia / kg for 15~30 days for tests of delayed-type hypersensitivity (DTH) induced by 2-dinitro fluoro benzene (DNFB), serum haemolysin, and carbon clearance. The results showed that the medium and high doses enhanced cellular immunity of mice significantly, and all doses enhanced significantly humoral immunity and phagocytosis by uninucleate macrophages with obvious dose dependence. All these results suggests that the capsule are of substantial immunoregulation function.