白细胞介素-11研究和开发进展

Progress in Research and Development of Interleukin-11

白细胞介素１１ 是美国ＦＤＡ 在１９９７ 年批准的第一个促血小板生成的细胞因子药品。本文就促血小板生成类细胞因子的Ｒ＆ Ｄ、ＩＬ１１ 基因与蛋白结构、ＩＬ１１ 生物学活性、药学研究以及临床应用作一综述。

Interleukin eleven(IL\|11) has been approved by FDA as the first thrombopoietic growth factor drug.This article summarizes four aspects:1.R&D of thrombopoietic growth factors.2.IL\|11 gene and protein structure.3.Biological activity of IL\|11.4.Pharmacology study and clinical application of IL\|11.\;