电针结合穴位注射治疗多发性硬化对照研究

Controlled research on multiple sclerosis treated with electroacupuncture and acupoint injection

目的:观察电针和穴位注射结合治疗多发性硬化(MS)的临床疗效。方法:应用区组随机化方法将40例患者分为电针组和电针加穴注组,每组20例。电针组采用电针治疗,穴取相应夹脊穴、委中、承山等;电针加穴注组在电针治疗基础上加穴位注射鼠神经生长因子,观察治疗前后两组患者日常生活能力(ADL)、扩展神经功能障碍评分(EDSS)的变化,以判定疗效。结果:电针组、电针加穴注组两组MS患者经治疗后EDSS评分分别为(4.23±1.21)分、(3.01±1.31)分,Barthel指数评分分别为(75.25±6.25)分、(83.11±8.45)分,均有显著疗效(均P<0.01),两组疗效比较电针加穴注组优于电针组(均P<0.01)。结论:电针结合穴位注射鼠神经生长因子治疗多发性硬化对于减轻残障、改善生活质量疗效显著。

Objective To observe the clinical efficacy of multiple sclerosis （MS） treated with electroacupunc- ture and acupoint injection. Methods The block randomization method was used to divide 40 cases into an elec- troacupuncture （EA） group and an EA ＋acupoint injection （AI） group, 20 cases in each one. In the EA group, EA was used at corresponding Jiaji （EX-B 2）, Weizhong （BL 40）, Chengshan （BL 57）, etc. In the EA＋ AI group, on the basis of EA, the acupoint injection of mouse nerve growth factor was supplemented. The activity of daily life （ADL） and expanded disability status score （EDSS） were observed in the two groups before and after treatment for the evaluation of the efficacy. Results The efficacy was achieved on MS after treatment in both groups （P〈0.01）. After treatment, the scores of EDSS and Barthel index were （3.01 ± 1.31） and （83. 11±8.45） in the EA＋AI group, which were better than those of （4.23±1.21） and （75.25±6.25） in the EA group （both P〈0.01）. Conclusion EA and AI co-act on reducing disability and improving the life quality in the treat- ment of MS and have achieved coordinately the significant effects.