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IL-17与类风湿性关节炎的研究进展 被引量:8

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摘要 类风湿性关节炎(RA)以滑膜细胞增生、新生血管形成以及局部大量T细胞的浸润为特点,结局均不同程度出现滑膜炎症、关节软骨、骨和关节囊破坏,最终导致关节畸形和功能丧失。以往研究证实,白介素(IL-1β)和肿瘤坏死因子(TNF-α)是炎症及关节损伤的重要介质,
出处 《中国中医骨伤科杂志》 CAS 2013年第9期67-69,共3页 Chinese Journal of Traditional Medical Traumatology & Orthopedics
基金 上海市浦江计划(10PJ1409300) 上海市自然科学基金(09ZR1432000) 国家自然基金(81173357) 上海高校创新团队(第二期)建设项目(沪教委科[2009]6号 26号文件) 上海市浦东新区卫生系统重点学科群建设项目(PWZxkq2011-01) 上海体育学院省部级重点实验室开放基金(yk2012002)
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