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Progestogens and early pregnancy： prevention and treatment 被引量：3

Progestogens and early pregnancy: prevention and treatment
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摘要 During human and mammalian pregnancy,endogenous progesterone is the dominant hormone since it is not only essential for conception and implantation,but also needed throughout pregnancy.Progesterone provided the effects of prevention and treatment in human pregnancy by certain mechanisms.If one considers prevention or treatment with progestogens in human pregnancy,that all progestogens are progestogenic,if one condsiders the progestogens for prevention and therapeutic approaches,nowadays,only two progenstogens can be considered fully suitable for prevention and treatment in human pregnancy:progesterone and dydrogesteone.This review introduced the mechanism of progesterone and dydrogesterone in pregnancy and treatment in human. During human and mammalian pregnancy, endogenous progesterone is the dominant hormone since it is not only essential for conception and implantation, but also needed throughout pregnancy. Progesterone provided the effects of prevention and treatment in human pregnancy by certain mechanisms. If one considers prevention or treatment with progestogens in human pregnancy, that all progestogens are progestogenic, if one condsiders the progestogens for prevention and therapeutic approaches, nowadays, only two progenstogens can be considered fully suitable for prevention and treatment in human pregnancy： progesterone and dydrogesteone. This review introduced the mechanism of progesterone and dydrogesterone in pregnancy and treatment in human.
作者 Adolf E. Schindler
机构地区 Institute for Medical Research and Education
出处 《首都医科大学学报》 CAS 2013年第4期492-493,共2页 Journal of Capital Medical University
关键词 妊娠过程 激素 孕酮 孕妇 progesterone dydrogesteone pregnancy
分类号 R135 [医药卫生—劳动卫生] R692 [医药卫生—泌尿科学]
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参考文献9

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  • 2Schindler A E, Campagnoli C, Druckmann R, et al. Clas?sification and pharmacology of progestins[J]. Maturitas, 2008,61(1-2) :171-180.
  • 3Kumar P, Magon N. Hormones in pregnancy[J]. Niger MedJ, 2012,53(4) :179-183.
  • 4Rayhupathy R, Al Mutawa E, Makhseed M, et al. Modula- tion of cytokine production by dydrogesterone in lymphocytes from women with recurrent miscarriage[J]. BJOG, 2005, 112(11) :1-6.
  • 5Skekeres-BarthoJ, WilczinskiJ R, Baste P, et al. Role of progesterone and progestin therapy in threatened abortion and preterm labor[J]. Front Biosc, 2008,13: 1981- 1990.
  • 6Arck P. et al. Early risk factors for miscarriage: a prospec?tive cohort study in pregnant women[J]. Reproductive Bi?omed Online, 2008,17 (1) : 101-113.
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同被引文献38

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首都医科大学学报
2013年 第4期

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