鼻鼽虚证患者鼻腔脱落细胞变化的临床观察

Clinical Observation of the Change of Exfoliated Cell in Nasal Cavity in Nosebleed and Deficiency Syndrome Patient

目的：探讨鼻衄虚证患者鼻腔脱落细胞的变化情况。方法：对变应性鼻炎中医辨证为肺气虚、脾气虚及肾阳虚的113例患者的鼻腔进行脱落细咆检查。结果：变应性鼻炎患者鼻分泌物中可见嗜酸性粒细胞。脾虚组、-肾虚组、对照组的中性粒细胞比重较大，脾虚组和对照组比较有显著性差异，而肾虚组出现了嗜酸性脱落细胞，男女出现概率为16．6％7及28．6％，变态反应症状越重及全身气虚、阳虚证症状越明显，则炎性反应越重，中性粒细胞比重越犬，出现嗜酸性脱落细胞的阳性率越高。结论：鼻腔脱落细胞中的上皮细胞、中性粒细胞及嗜酸性粒细胞的变化可作为变应性鼻炎患者中医辨证分型的参考客观指标。

Objective： To explore the change of exfoliated cell in nasal cavity in nosebleed and deficiency syndrome patient. Methods： 113 patients with allergic rhinitis were divided into insuffi- ciency of lung-qi group, deficiency of spleen-qi group and deficiency of kidney-yang group. All of them were proceeded cytoscopy of exfoliated cell in nasal cavity. Results： The excreta of allergic rhinitis patients had eosnophils. The proportion of neutrophil was large in deficiency of spleen-qi group, deficiency of kidney-yang group and control group. The comparison between deficiency of spleen-qi group and control group had significant difference. Deficiency of kidney-yang group ap- peared eosinophilic, and the occurrence probability of men and women were 16.6% and 28.6%. The symptoms of allergic reaction, systemic deficiency of qi and yang deficiency were more obvious, the inflammatory reaction was heavier the proportion of neutrophil was large, the positive rate of oc- curring eosinophilic was higher. Conclusion： The change of epithelial cell, neutrophil and eosno- phils of exfoliated cell in nasal cavity can become the referenced objective indicators to classify al- lergic rhinitis through syndrome differentiation of TCM.