地佐辛用于剖宫产术后静脉镇痛300例临床效果评价

A Survey of Effect of Dezocine for Obstetric of Postoperative Analgesia 300 Cases

目的:观察地佐辛用于剖宫产术后静脉镇痛的疗效。方法:将我院行剖宫产的正常足月产妇300例随机分成A、B两组,分别给予芬太尼+托烷司琼和芬太尼+托烷司琼+地佐辛进行术后静脉镇痛,比较两组的镇痛效果,分别记录静息/咳嗽出室时、术后6 h、12 h、24 h的VSA评分并进行比较,采用Bromage评分评价患者运动阻滞恢复情况,同时记录患者术后肛门排气时间以及不良反应等。结果:A组产妇出室时、术后6 h、12 h、24 h小时静息VSA评分均高于B组,(P<0.01);咳嗽时各点VSA评分A组高于B组,(P<0.05),差异有统计学意义;A组产妇术后恢复至Bromage 0级平均用时(5.9±2.4)h,B组恢复至Bromage 0级平均用时(5.1±2.1)h,(P<0.01),差异有统计学意义;A组产妇术后出现头晕嗜睡、尿潴留、恶心呕吐等不良反应明显高于B组,(P<0.01),差异有统计学意义。结论:地佐辛用于产科术后镇痛效果好,术后患者恢复时间短,且不良反应较小。

Objective： To observe the efficacy of Dezocine on the treatment of intravenous analgesia after cesarean sectiorL Methods： 300 case normal term maternal in our hospital cesarean section were randomly divided into groups A and B, were given Fentanyl＋ Tropisetron and Fen- tanyl＋Tropisetron＋Dezocine postoperative analgesia. Analgesic effect were compared and recorded at rest / cough out of room, and VSA score after 6h, 12h, 24h were compared, the Bromage scale of patients with motor block were evaluated, and pa- tients with anal exhaust time and adverse were recorded. Results： When puerperae in A group were out of room and had rest after 6h, 12h, 24h hours, VSA scores were higher than that in group B（P〈0.01）, cough VSA in A group is still higher than that in group B（P〈0.05）, the difference was statistically significant; the average time of Group A maternal postoperative for restoring to Bromage 0 level is （5.9 ＋ 2.4） h, that of Group B is （5.1 ＋ 2.1） h, P〈0.01, the difference was statistically significant; The maternal postoperative dizziness, drowsi- ness, urinary retention, nausea, vomiting and other adverse reactions in group A was significantly higher than those in group B, P〈0.01. The difference was statistically significant. Conclusion： Dezocine for obstetric postoperative analgesia and analgesic effect, postoperative recovery time is short, and adverse reactions is few.