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Lack of Association between Genetic Polymorphisms Affecting Autonomic Activity and Coronary Artery Spasm

Lack of Association between Genetic Polymorphisms Affecting Autonomic Activity and Coronary Artery Spasm
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摘要 Coronary artery spasm (CAS) is one of the leading pathological causes of a wide spectrum of ischemic heart diseases, ranging from variant angina pectoris to acute myocardial infarction and even sudden cardiac death[1]. Furthermore, Pierron et al. concluded that CAS of angiographically normal or sub-normal arteries is responsible for death or myocardial infarction in 11.6% of all cases. Oddly, the incidence of CAS is remarkably higher in Asians than in Caucasians[3], suggesting genetic involvement In its pathogenesis. Coronary artery spasm (CAS) is one of the leading pathological causes of a wide spectrum of ischemic heart diseases, ranging from variant angina pectoris to acute myocardial infarction and even sudden cardiac death[1]. Furthermore, Pierron et al. concluded that CAS of angiographically normal or sub-normal arteries is responsible for death or myocardial infarction in 11.6% of all cases. Oddly, the incidence of CAS is remarkably higher in Asians than in Caucasians[3], suggesting genetic involvement In its pathogenesis.
出处 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2013年第8期689-692,共4页 生物医学与环境科学(英文版)
基金 supported by fund from Guangdong Natural Science Foundation (No. 9251001002000002)
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参考文献10

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