摘要
目的:了解首都医科大学大兴医院中成药、中药注射剂发生药品不良反应(ADR)的情况,了解中成药、中药注射剂发生ADR的特点及规律,探讨临床用药注意事项,促进临床合理用药。方法:采用自发呈报的方式,由临床医师、护士及临床药师填写ADR报表,收集2010—2012年我院166例中成药、中药注射剂ADR报告,并利用Excel表格统计和手工筛选的方法,对患者年龄、ADR类型及表现等有关数据进行分类统计、分析。结果:166例ADR中,60岁以上的老年患者为66例(占39.75%),51～60岁患者为53例(占31.92%);ADR以皮肤及附件损害为最常见,有43例,占25.9%。结论:应辩证看待中成药及中药注射剂ADR,加强ADR监测工作,改进处方及护理行为,提高临床用药安全,避免ADR发生,使中成药及中药注射剂的使用更加合理。
OBJECTIVE ：To analyze the status quo, characteristics and associated factors of adverse drug reactions （ADRs） induced by Chinese traditional patent medicine or traditional Chinese medicine injections in Daxing Hospital of Capital Medical University and investigate the precautions in clinical medication so as to promote clinical rational use of drug. METHODS： By voluntary reporting, the ADR report forms were filled in by clinicians, nurses and clinical pharmacists. A total of 166 ADR cases induced by Chinese traditional patent medicine or traditional Chinese medicine injections collected in our hospital during 2012-2012 were analyzed statistically with regard to patients＇ age, ADR type and ADR manifestation by using EXCEL combined with manual screening. RESULTS ： Of the total 166 ADR cases, 66 （39.7%） aged above 60 years and 53 （31.92% ）aged 51-60 years; 43 （25.9%）manifested as lesions of skin and its appendants. CONCLUSION： The ADR induced by Chinese traditional patent medicine or traditional Chinese medicine injections should be viewed dialectically. It＇s necessary to tighten ADR monitoring, improve the behavior of prescribing and nursing and improve clinical drug safety to avoid ADR occurrence and achieve more rational use of Chinese traditional patent medicine and traditional Chinese medicine injections.
出处
《中国医院用药评价与分析》
2013年第8期738-741,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
中成药
中药注射剂
药品不良反应
合理用药
Chinese traditional patent medicine
Traditional Chinese medicine injections
Adverse drug reaction
Rational use of drug
