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浅析抑肽酶对脑外科手术患者的血液保护作用 被引量:3

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摘要 目的观察分析不同剂量抑肽酶应用于脑外科手术对患者血液保护作用。方法选择颅脑外科手术126例,将其分为三组:A组为小剂量抑肽酶组,B组为大剂量抑肽酶组,C组为对照组,观察血液保护作用。结果 A组、B组较C组术中出血量、术后24h引流量以及术中及术后24h输血量明显减少(P<0.05);3组术前凝血功能的检查(血小板计数、凝血酶原时间、活化部分凝血活酶时间、血浆纤维蛋白原含量)比较(P>0.05)差异无统计学意义;A、B组与C组术后凝血功能的检查指标比较(P<0.05)差异有统计学意义。结论抑肽酶对脑外科手术患者的血液保护作用明显,使围术期出血及异体输血减少,小剂量抑肽酶与大剂量抑肽酶同样有效。但小剂量更安全、经济。
作者 焦文峰
出处 《中国实用医药》 2013年第24期119-120,共2页 China Practical Medicine
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