重复经颅磁刺激对精神分裂症的影响

Effect of Repetitive Transcranial Magnetic Stimulation on Blood Stasis of Schizophrenia

目的:探讨重复经颅磁刺激治疗精神分裂症的临床疗效。方法:将61例血瘀证精神分裂症患者按随机数字表法分为治疗组31例和对照组30例。对照组采用利培酮或奥氮平口服治疗,治疗组在对照组的基础上用重复经颅磁刺激治疗,对两组采用中医症状分级量表进行临床血瘀证候群疗效评定;采用副反应量表(TESS)进行评定不良反应。结果:治疗组疗效明显优于对照组,有显著性差异(P<0.05);治疗组不良反应的发生明显少于对照组,亦有显著性差异(P<0.01)。结论:重复经颅磁刺激能够有效改善血瘀证精神分裂症的血瘀证候群症状,减少不良反应发生几率,具有活血化瘀功效。

Objective ：To investigate the clinical curative effect of Repetitive transcranial magnetic stimulation in the treatment of blood stasis of schizophrenia. Methods ：61 cases with schizophrenia blood stasis were randomly divided into treatment group and control group. The control group was given oral treatment of olanzapine or risperidone and the treatment group was given repetitive transcranial magnetic stimulation based on the control group. Use traditional Chinese medicine symptom rating scale for curative effect evaluation and side effect scale（TESS） to assess adverse reactions. Results：The curative effect of treatment group was better than control group. The difference was statistically significant （ P 〈 0.05 ）. The adverse reactions in treatment group were significantly lower than that in control group. The difference was also statistically significant（ P 〈 0.01 ）. Conclusion：Repetitive transeranial magnetic stimulation can effectively improve blood stasis syndrome of blood stasis type schizophrenia, reduce the adverse reaction occurrence and activate blood circulation to dissipate blood stasis as well as provide clinical basis for further exploration of the efficacy of traditional Chinese medicine principle of repetitive transcranial magnetic stimulation.