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紧密连接的分子结构、生物学功能及其信号调控 被引量：3

Molecular Structure and Biological Function of Tight Junction and Its Signal Regulation
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摘要 上皮紧密连接是由occludin、claudins、ZOs等构成的相邻细胞间连接复合体,且紧密连接与胃肠道营养物质吸收、微生物黏附关系以及维持上皮细胞通透性和屏障作用等最为密切。主要对紧密连接的分子结构、生物学功能及其信号调控方面的内容进行了综述。 Epithelial tight junction is an intercellular junctional complex that is composed of occludin, claudins and ZOs, etc. The tight junction is closely related with gastrointestinal nutrition absorption ,microbial adhesion, the permeability and barrier function of epithelial cell. The molecular structure, biological function and signal regulation of tight junction were reviewed.
作者 马燕芬 红梅 格根塔娜 张春华
机构地区 内蒙古农牧业科学院动物营养与饲料研究所 内蒙古林西县农牧业局
出处 《畜牧与饲料科学》 2013年第7期39-41,共3页 Animal Husbandry and Feed Science
基金 公益性行业(农业)科研专项(200903003) 内蒙古农牧业科学院青年创新基金(2012QNJJM01)
关键词 紧密连接 分子结构 生物学功能 信号调控 tight junctions molecular structure biological function signal regulation
分类号 Q7 [生物学—分子生物学]
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参考文献9

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同被引文献28

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  • 8TURNER J R. Molecular basis of epithelial barrier regula- tion:from basic mechanisms to clinical application[J]. The Amer- ican Journal of Pathology,2006, 169(6) : 1901-1909.
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  • 10CAPALDO C T, NUSRAT A. Cytokine regulation of tight junctions[J]. BiochimBiophys Acta,2009,1788(4) :864-871.

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畜牧与饲料科学
2013年 第7期

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