吡唑磺酰氨基甲酸酯的合成

Synthesis of ethyl 5 [(ethoxycarbonyl) aminosulfonyl] 1 methyl pyrazole 4 carboxylate

为合成除草剂吡嘧磺隆的中间体 ,提出了非光气法合成 5- [(乙氧羰基 )氨基磺酰基 ]- 1 -甲基吡唑 - 4-羧酸乙酯 (简称吡唑磺酰氨基甲酸酯 )的新方法 ,由 5-氯磺酰基 - 1 -甲基吡唑 - 4-羧酸乙酯 (简称氯磺酰基吡唑 )与氰酸钠反应 ,再醇解制得 ,收率约 75%。产品经元素分析、IR、1H

Ethyl 5 [(ethoxycarbonyl)aminosulfonyl] 1 methyl pyrazole 4 carboxylate was prepared by a new method, using ethyl 5 (chlorosulfonyl) 1 methyl pyrazole 4 carboxylate, sodium cyanate and ethyl alcohol as starting materials. The yield is 75%. The product has been confirmed by element analysis, IR and 1H NMR.