改良甲状腺次全切除术治疗甲状腺功能亢进临床疗效分析

Clinical study on modified subtotal thyroidectomy in treatment of 68 patients with hyperthyroidism

目的探讨改良甲状腺次全切除术治疗甲状腺功能亢进的临床效果。方法将收治的68例甲状腺功能亢进患者,随机分为对照组和观察组,对照组采用甲状腺次全切除术治疗,观察组采用改良甲状腺次全切除术治疗。比较两组治疗时间、术中出血量、平均住院时间及不良反应发生情况。结果观察组手术时间、术中出血量及平均住院时间显著少于对照组,差异有统计学意义(P<0.05)。对照组不良反应发生率26.5%,复发率11.8%。观察组未见明显不良反应发生,未见复发患者。观察组不良反应发生率及复发率显著低于对照组,差异有统计学意义(P<0.05)。结论采用改良甲状腺次全切除术治疗甲状腺功能亢进,手术时间、术中出血量及患者住院时间显著少于甲状腺次全切除术,不良反应少,复发率低,值得临床推广应用。

Objective To explore the clinical effect of modified subtotal thyroidectomy in treatment of 68 patients with hyperthyroidism. Methods A total of 68 patients with hyperthyroidism were randomly divided into control group and observation group. Patients in control group were treated with subtotal thyroidectomy, and patients in observation group were treated with modified subtotal thyroidectomy. The operating time, peri -operative bleeding, the mean hospitalization days and adverse reactions were compared between these two groups. Results The operating time, amount of peri - operative bleeding and average hospitalization days of patients in observation group were significantly less than those of patients in control group, their difference was statistically significant （ P 〈 0.05 ）. The rates of adverse reactions and recurrence in observation group were 26.5 % and 11.8% respectively. There was no obvious adverse reaction and recurrence oecurrod in patients of observation group. Conclusion Modified subtotal thyroideetomy is best choice for surgical treatment of patients with hyperthyroidism, and its operating time, amount of peri - operative bleeding, hospitalization time and adverse effects are significantly less than those with conventional subtotal thyroidectomy, hence it is worthy to be applied in clinical practice.