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糖尿病乳酸酸中毒21例临床分析 被引量:3

Diabetic lactic acidosis: A clinical analysis of 21 cases
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摘要 目的探讨糖尿病乳酸酸中毒的诱发因素、临床特点及治疗进展。方法对近两年收治的糖尿病乳酸酸中毒患者的临床特点及诊疗资料进行回顾性分析。结果 21例患者中,6例好转出院,15例先后死亡。结论糖尿病乳酸酸中毒多发于老年女性,与血糖控制不良、双胍类降糖药及感染等诱因有关,临床表现不典型,常合并多种基础疾病,多采用综合支持治疗,死亡率较高。 Objective To investigate the inducement, clinical features and treatment progress of diabetic lactic acido sis. Methods The clinical data of 21 cases for diabetic lactic acidosis were analyzed retrospectively. Results Among the consulted 21 cases, 6 cases were cured and 15 cases died successively. Conclusion Diabetic lactic acidosis often happens to elderly female and caused because of some inducing factors such as failed blood glucose control, biguanides hypoglycemic drugs, infection, etc. Besides, its clinical manifestation is not typical, combined with various of underlying diseases and is usually cured by comprehensive treatment, which causes the result that the motality is quite high.
出处 《中国现代医生》 2013年第26期153-154,共2页 China Modern Doctor
关键词 糖尿病 乳酸酸中毒 临床特点 诊断 治疗 Lactic acidosis Diabetes Clinical feature Diagnosis Treatment
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  • 1肖新华.糖尿病乳酸性酸中毒[J].内科急危重症杂志,2005,11(4):151-153. 被引量:20
  • 2于华众,李章平,吴朝明,程俊彦,陈寿权.服用二甲双胍的糖尿病患者乳酸酸中毒的特点分析[J].实用医学杂志,2006,22(7):804-805. 被引量:14
  • 3陈灏珠,林果为.实用内科学[M].13版.北京:人民卫生出版社,2009:919.
  • 4Holanda Pena MS,Suberviola Canas B,Gonz á lez Castro A,et al.Severe lactic acidosis associated to metformin intoxication.Nutr Hosp,2007,22(1):124-125.
  • 5Millican S,Cottrell N,Green B.Do risk factors for lactic acidosis influence dosing of metformin? J Clin Pharm Ther,2004,29 (5):449-454.
  • 6Yang PW,Lin KH,Lo SH,et al.Successful treatment of severe lactic acidosis caused by a suicide attempt with a metformin overdose.Kaohsiung J Med Sci,2009,25(2):93-97.
  • 7Pongwecharak J,Tengrneesri N,Malanusorn N,et al.Prescribing metformin in type 2 diabetes with a contraindication:prevalence and outcome.Pharm World Sci,2009,31(4):4,81-486.
  • 8Legrand D,Scheen AJ.Multiple risk factors and drug interactions leading to severe lactic acidosis.Therapie,2008,63(1):69-70.
  • 9Di Grande A,Vancheri F,Giustolisi V,et al.Mefformin-induced lactic acidosis in a type 2 diabetic patient with acute renal failure.Clin Ter,2008,159(2):87-89.
  • 10Seidowsky A,Nseir S,Houdret N,et al.Mefformin-sssociated lactic acidosis:a prognostic and therapeutic study.Crit Care Med,2009,37(7):2312-2313.

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  • 1陈灏珠.实用内科学[M].北京:人民卫生出版社,2009.
  • 2葛均波,徐永健.内科学[M].第8版.北京:人民卫生出版社,2013.259~265.
  • 3Jansen T C, van Bommel J, Woodward R, et al.Association between blood lactate levels, Sequential Organ Failure Assessment subscores, and 28- day mortality during early and late intensive care unit stay: A retrospective observational studvfJl.Crit Care Med, 2009, 37(8): 2369-2374.
  • 4Krzymiefi J, Karnafel W.Lactic acidosis in patients with diabetes[J].MedSci, 2013, 123(3): 91-97.
  • 5Yeung C W, Chung H Y, Fong B M, et al.Metformin-Associated Lactic Acidosis in Chinese Patients with Type II Diabetes[J].Pharmacology, 2011, 88(5-6): 260-265.
  • 6Zhang Q C, Fang X B, Cai Z X, et al.Treatment of lactic acidosis with early continuous blood purification[J].Zhonghua Wei Zhong Bing Ji Jiu Yi Xue, 2013, 25(1): 45-47.
  • 7Peters N, Jay N, Barraud D, et al.Mefformin-associated lactic acidosis in an intensive care unit[J].Cfitical Care, 2008, 12(6): 1-5.
  • 8马晓飞.从实践到指南-糖尿病血糖控制目标探讨[J].中外医学研究,2011,9(9):92-94. 被引量:2
  • 9高伟波,朱继红.乳酸性酸中毒与危重症[J].疑难病杂志,2011,10(2):161-163. 被引量:28
  • 10郑鹏,杨卫,韩乔燕,张文青.乳酸酸中毒12例临床分析[J].实用临床医药杂志,2011,15(13):105-106. 被引量:3

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