中西医结合治疗强直性脊柱炎的效果观察

Clinical efficacy observation of ankylosing spondylitis treated with combination of traditional Chinese and western medicine

目的观察中西医结合治疗强直性脊柱炎的效果。方法选取本院2010年2月2012年6月收治的160例强直性脊柱炎患者为研究对象,将其随机分为对照组和治疗组,每组80例,对照组患者给予单纯西药治疗,治疗组在此基础上加用中药治疗,疗程结束后对比分析两组患者的疗效。结果治疗组治疗总有效率明显高于对照组(P<0.05),两组患者晨僵时间、C反应蛋白(CRP)、红细胞沉降率(ESR)等临床指标和治疗前相比有明显的改善(P<0.05),但治疗组改善情况明显优于对照组(P<0.05),两组患者主要不良反应为胃肠道反应,差异无统计学意义(P>0.05)。结论强直性脊柱炎采用中西医结合治疗疗效确切,安全性高,可明显改善患者相关的临床症状,值得在临床上推广应用。

Objective To observe curative effect of combination of traditional Chinese and western medicine in treat- ment of ankylosing spondylitis.Methods 160 cases with ankylosing spondylitis in our hospital from February 2010 to June 2012 were selected.Patients were randomly divided into control group and treatment group,80 cases in each group.Control group only received western medicine.On this basis, treatment group received western medicine.After pe- riod of treatment,curative effects of two groups were compared.Results Total effective rate of treatment group was obvi- ously higher than that of control group （P〈0.05）.Compared clinical indicators after treatment with before treatment, morning stiffness time,CRP,ESR had improved significantly,but the curative effect of symptoms in the treatment group was significantly better than that of the control group （P〈0.05）.The main adverse reaction for two groups was gas- trointestinal tract reaction.There was no significant difference （P〉O.05）,Conclusion Traditional Chinese and western medicine for ankylosing spondylitis has definite curative effect and safe.They can ameliorate the clinic symptoms of patients obviously.It is worthy of clinical application.