摘要
通常在运动末期 ,NK细胞的数量会显著增加 ,这可能是由于儿茶酚胺介导和细胞聚集作用所致。运动后 ,细胞数量持续几小时下降 ,低于正常水平的一半 (某些特殊条件下的运动如过度训练、大强度运动等除外 ) ,2 4小时内可恢复到正常水平。若是大强度的运动 ,NK细胞的数量和活性在运动过程中便开始减少 ,尽管幅度很小 ,但对于一些一周训练几次的运动员来说 ,这种降低长期积累可能会损害其免疫系统的功能。也有人认为 ,经长期运动训练 ,人体安静时的 NK细胞数量及活性会升高 ,但仍需进一步的证实。
In general, there was a marked inerease in NK cell count at the end of exercise, probably attributed to a catecholamine-mediated demargination of cells. Following exercise, cell counts are dropped to less than half of normal levels for a couple of hours, except in unusual circumstances, normal resting values are restored whin 24 hours. Although the usual depression of NK cell count seems too brief to have major practical importamce for health, there could be cumulative adverse effect on immuno surveillunce thank and health experience on athletes who induce such changse several times per weak. There is a week suggestion of an offsetting inerease on resting NK cell counts and cytolytic action in trained individuals, and this merits further exploration in studies where effects of recent training sessions are carefully controlled.
