腔隙性脑梗死合并颅内动脉狭窄的临床特点研究

Study of the clinical features of intracranial artery stenosis in lacunar infarction patients

目的分析腔隙性脑梗死合并颅内动脉狭窄的临床特点。方法将174例腔隙性脑梗死患者分为颅内动脉狭窄组和无颅内动脉狭窄组,分析两组患者一般资料、危险因素及短期神经功能改善等情况。结果 174例患者中合并颅内动脉狭窄118例(67.8%),平均年龄(63.89±11.17)岁,合并高血压病120例(68.9%),冠心病62例(35.6%),高脂血症98例(56.3%)。冠心病、糖尿病是颅内动脉狭窄的腔隙性脑梗死患者的危险因素,无颅内动脉狭窄组的患者血高密度脂蛋白(HDL)水平高、短期神经功能改善好。结论腔隙性脑梗死患者合并颅内动脉狭窄的比率高,颅内动脉狭窄的腔隙性脑梗死患者多合并冠心病、糖尿病,无颅内动脉狭窄的患者血HDL高,短期神经功能改善好。

Objective To analysis the clinical features of intracranial artery stenosis in lacunar infarction patients. Method It was divided into group A（ intracranial artery stenosis group） and group B（ no stenasis） for 174 lacunar infarction patients, such as basic information, risk factors and short-term improving neural function defect were taken into consideration. Result There were 118 （67.8%） patients with intracranial artery stenosis in 174 lacunar infarction patients. The average age was （63.89-＋ 11.17） years old. And 120 cases（68.9% ） with hypertension,62 cases （ 35.6% ） with coronary disease,98 cases （ 56.3 % ） with hyperlipemia. Coronary disease （ OR = 1.135,95% CI = 1. 003 - 1. 284, diabetes mel]itus （ OR = 1. 135,95 % CI = 1. 003 - 1. 284 ） were preferentially related to lacunar infarction patients of group A, whereas high HDL values （OR= 1. 135, 95% CI= 1. 003 - 1. 284） ,better short-term improving neural function defect（ OR= 1. 135,95% CI = 1. 003 - 1. 284 ） were related to group B. Conclusion The rate of lacunar infarction patients with intracranial artery stenosis is high. Lacunar infarction patients with intracrani- al artery stenosis are more likely with coronary disease, diabetes mellitus, other patients have high HDL values, better short-term improving neural function defect.