UAE治疗子宫腺肌病中对卵巢功能影响的临床研究

Clinical study on ovarian functionof patients with adenomyosis after uterine artery embolization

目的:探讨PVA颗粒在子宫动脉栓塞治疗子宫腺肌病中的临床疗效及对卵巢功能影响。方法:回顾性分析89例子宫腺肌病患者在采用PVA颗粒行子宫动脉栓塞术治疗(UAE)前及治疗后3个月、6个月的月经、雌二醇(E2)、卵泡刺激素(FSH)及黄体生成素(LH)变化情况。结果:所有患者均完成双侧子宫动脉栓塞治疗,栓塞治疗后临床症状缓解明显,各时间段激素水平变化无统计学意义(P>0.05)。结论:PVA颗粒应用在子宫动脉栓塞治疗子宫腺肌病中对卵巢功能无明显影响,是一种简单、安全、有效的治疗方法。

Objective：Tostudy theeffectofPVA particleson the treatment of adenomyosisand ovarian function. Meth- ods：Retrospective analysis 89 cases ofPVA particlesfor treatment of adenomyosis change ofmenstruation,estradiol （E2）, follicle-stimulating hormone （FSH） and luteinizing hormone （LH） before and3months and 6monthsafter treatment. Re- suits：All patients were treated bybilateral uterine artery embolization,and clinical symptoms relieve obviousafter the embolization therapy,level changes of hormone each time hasno statistical significance （P〈0.01）. Conclusions：PVA particles are used in uterine artery embolization for treatment of adenomyosis, which has no significant influence on o- varian function, and is a simple, sa/e and effective treatment method.