尿毒症患者血透治疗后心功能检测结果的临床分析

Clinical Analysis of Heart Function After Uremia Hemodialysis

目的:观察、分析尿毒症患者血液透析后左室结构功能的改变及其相关因素。方法:选取尿毒症患者139例,对比血液透析治疗后患者的彩色多普勒超声仪检测参数,分析心脏结构和功能的改变。结果:139例尿毒症患者血透后的心功能检测结果:年龄<50岁组与≥70岁组对比,左室结构和功能相关的IVSd、IVSs、LVPWd、LVPWs有显著性差异(P<0.05),提示随年龄的增长,室间隔及左室后壁厚度变薄。性别与左室结构和功能的关系无明显改变。血透时间<12个月组与≥36个月组对比,LVPWd、LVPWs有显著性差异(P<0.05),提示血透时间延长,室间隔及左室后壁厚度增厚。结论:随着血透患者的年龄、透析时间的增加,尿毒症血透患者左心室功能逐渐改变,影响尿毒症维持性血液透析(MHD)患者心功能的因素主要是血透时间和患者的年龄,透析时间越长,心功能越差,患者的年龄越大,心肌细胞凋亡越多,代谢功能越差,与性别无关。

Objective：The objective was to observe and analyse the left heart structure and function change after the hemodialysis of the uremia patients and the relative factors.Methods：The methods were to collect 139 eases of the uremia patients from hospitals and the control group, and to compare the echocardiography change of the uremia pa- tients group and the contol group, then to analyse the heart structure change and function change after the hemodialy- sis. Result：We found that for the left heart structure and function in the 〈50 years old patients and ~〉70 years old pa- tients of the 139 eases of the uremia patients group, the IVSd,IVSs,IVPWd,LVPWs had a signsfieant difference （P〈0.05） between the 〈50 years old patients and I〉 70 years old patients.The heart thickness of the 〈50 years old pa- tients and the heart thickness of ~〉 70 years old patients were gradully reduced with the age going up.The relationship of the patients sex and the left heart structure and function did not makedly change. In the hemodialysis time 〈12 months group and 〉36 months group, the IVPWd,LVPWs had an increasing with the hemodialysis time going up and a significant difference （P〈O.O5）.Conclusion：By the increation of the age and the hemodialysis time the hemodialysis uremia patients had a reducing change of the left heart function. The main factors influening the patients left heat function were the hemodialysis time and the age. The longer hemodialysis time, the worse the left heart function.The older, the more left heart cells apoptosis, and the worse the heart metabolic function, bearing no relationship with the oatients sex.