头孢布烯对淋球菌的药敏试验与治疗无合并症淋病的疗效

Disk Susceptibility Test of Ceftibuten for Clinical Strains of Gonorrhea Neisseria and Efficacy of Ceftibuten in the Treatment of Non complication Gonorrhea

目的 了解头孢布烯对淋病奈瑟球菌的抗菌活性和治疗淋病的疗效。方法 使用头孢布烯治疗了 6 3例无合并症淋病 ,并采用药敏纸片法检测了上述病例的 6 3株淋球菌菌株对头孢布烯的药物敏感性。结果 6 3株临床淋球菌中高度敏感 48株 (76 .2 % ) ,中度敏感 7株 (11.1% ) ,低度敏感 8株 (12 .7% )。临床疗效 :治愈 5 6例 (88.9% ) ,有效 4例 (6 .3 % ) ,无效 3例 (4.8% )。结论 头孢布烯对淋球菌有较高的敏感性 。

Objective To explore the susceptibilities of clinical strains of Gonorrhea Neisseria to ceftibuten and efficacy of ceftibuten in the treatment of non complication gonorrhea.Methods Sixty three patients with non complication gonorrhea were treated by ceftibuten per oral.Disk diffusion test was applied to detect the susceptibilities of clinical strains of Gonorrhea Neisseria cultivated from these patients.Results Of 63 clinical strains of Gonorrhea Neisseria,48 strains (76.2%)were high susceptibility,7 strains(11.1%)middle susceptibility and 8 strains(12.7%)low susceptibility to ceftibuten.Efficacy of ceftibuten in the treatment of non complication gonorrhea:56 cases(88.9%)were cured,4 cases(6.3%) progress,3 cases(4.8%)fail.Conclusion Ceftibuten has relatively high susceptibility to clinical strains of Gonorrhea Neisseria and it will be an alternative therapy in the treatment of non complication gonorrhea.