重型颅脑损伤患者血钠水平的变化及与预后关系的探讨

Discussion on sodium level change in the severe traumatic brain injury patients and its relationship with prognosis

目的观察重型颅脑损伤(STBI)患者血钠水平的变化并探讨STBI患者血钠水平与预后的关系。方法选择38例STBI患者,根据患者入院时格拉斯哥昏迷评分(GCS)分为A组、B组和C组,观察以上各组患者住院后第1 d、第3 d、第5 d和第7 d血钠水平的变化;并依据患者就诊时血钠水平将以上患者分为正常组,轻度组,中度组和重度组,根据格拉斯哥预后评分(GOS),探讨STBI患者的血钠水平与预后的关系。结果入院后第1 d各组患者血钠水平与GCS评分呈负相关性,不同GCS评分患者间血钠水平差异具有统计学意义;就诊时患者血钠水平与病死率呈正相关性,不同血钠水平患者间病死率比较,差异差异具有统计学意义。结论就诊时STBI患者血钠水平与其病程进展和预后密切相关,应重视患者血钠水平的纠正。

Objective To observe the serum sodium levels change in the severe traumatic brain injury（STBI） patients and explore the relationship between sodium levels and prognosis in the severe traumatic brain injury patients. Method 38 STBI patients, according to the serum soduim level change observed in the 1 st, 3rd, 5th and 7th hospital day, they were divided into group A, group B and group C. They were subdevided into normal, mild, moderate and severe group. The relationship between sodium levels with prognosis and GCS score were explored. Result They were negative correlation between sodium levels and GCS scores. Conclusion The patient＇s serum sodium level is closely related to its progression and prognosis and should be our attention.