丁沉透膈散治疗化疗延迟呕吐临床观察

Clinical Observation on Dingchen Touge Powder for Delayed Chemotherapy-induced Vomiting

目的:观察中药丁沉透膈散治疗肿瘤化疗所致消化道反应的疗效。方法:将136例化疗所致延迟呕吐的患者随机分为2组,在化疗周期中实验组以中药丁沉透膈散汤剂口服;对照组予甲氧氯普胺+地塞米松,比较2组的临床效果与药物不良反应。结果:实验组在治疗食欲不振、抑制恶心、呕吐等方面明显优于对照组,差异有统计学意义(P值均小于0.05)。结论:中药丁沉透膈散防治化疗药物所致消化道反应综合疗效较好,值得临床推广应用。

Objective：To investigate the therapeutic effect of Dingchen Touge powder for chemotherapy induced gastrointestinal reaction.Methods：A total of 136 patients with delayed chemotherapy-induced vomiting were randomly divided into two groups,in chemotherapy cycle,treatment group was given Dingchen Touge powder orally;while control group was given methoxychlor tome amine and dexamethasone.Clinical effect and adverse reaction in two groups were observed and compared.Results：The effect for symptoms of anorexia,nausea and vomiting in treatment group was obviously superior to control group,and the difference was statistically significant（P 0.05）.Conclusion：Dingchen Touge powder has good comprehensive effect on chemotherapy-induced gastrointestinal reaction,and is worthy to be clinically popularized and applied.