期刊文献+

不同固定方式对腱-骨愈合界面影响的形态学研究 被引量:1

Effect of different fixations on tendon-bone healing interface: a morphological study
下载PDF
导出
摘要 背景:关节镜下重建交叉韧带已得到广泛应用,关于腱骨愈合状态的研究多集中在患肢功能恢复以及愈合程度及稳定性观察方面。目的:了解韧带重建过程中各种固定方式对肌腱-骨界面愈合的影响。方法:2009年7月至2009年9月以长白二号体重100千克左右的八头成年猪的双膝关节作为实验对象进行动物实验,采用四种固定方式对腱-骨进行固定,包括纽扣接骨板悬吊固定、肌腱包裹自体松质骨方式、界面挤压螺钉固定、横穿可吸收钉固定,对手术后6周、12周时界面愈合的情况进行病理切片观察。结果:纽扣接骨板固定模式腱骨界面愈合均匀,理论抗拉力大,相反固定物对腱骨界面干扰明显的界面愈合不理想,骨纤维细胞排列不整齐,理论拉力降低,尤其表现在界面挤压螺钉方面;对于有自体松质骨植入的在腱骨愈合过程中活性骨质坏死,无促进腱骨愈合的作用。结论:在腱骨愈合过程中界面固定方式对早期愈合有不同程度的影响,悬吊固定方式腱-骨愈合界面形态学表现理想。 Background: The reconstruction of cruciate ligament under arthroscope has been widely applied. Nowadays, the study on tendon-bone healing is mostly focused on function recovery of patients and stability of healing. Objective: The purpose of the study is to explore the influence of different fixed styles to tendon-bone healing in the process of ligament reconstruction. Methods: From July 2009 to September 2009, eight adult Landrace II pigs weighing 100 kg was used as experiment animal and divided into four groups (n=2). Four tendon-bone fixed methods were applied in both knee in each group respectively, including button-plate suspension fixation, autologous bone tendon wrapped mode, interface extrusion screw, and adsorb- able screw. The healing of interface was observed at 6 and 12 weeks postoperatively. Results: There was a large theoretical tensile strength for tendon-bone interface by button plate fixation. However, antolo- gous bone and screw interfered the healing of tendon-bone interface; fibrocytes were arranged irregularly and tensile strength was reduced, especially in the interface of extrusion screws. Conclusions: The fixation method of tendon can impact early bone healing. Tendon-bone healing by suspension fixation is better than other fixations in morphology.
出处 《中国骨与关节外科》 2013年第4期365-369,共5页 Chinese Journal of Bone and Joint Surgery
关键词 固定方式 腱-骨愈合 形态学 Fixation Tendon-bone healing Morphology
  • 相关文献

参考文献15

  • 1Shen W, Jordan S, Fu F. Review article: anatomic double bundle anterior cruciate ligament reconstruction. J Orthop Surg (Hong Kong), 2007, 15(2): 216-221.
  • 2黄华扬,丁焕文,刘景发,尹庆水,刘少喻.关节镜下自体髌腱重建前交叉韧带及有关问题的探讨[J].中华骨科杂志,1999,19(5):275-277. 被引量:14
  • 3Yosmaolua HB, Baltacl G, Kaya D, et al. Comparison of functional outcomes of two anterior cruciate ligament re- construction methods with hamstring tendon graft. Acta Or- thop Traumatol Turc, 2011, 45(4): 240-247.
  • 4Petersen W, Laprell H. Insertion of autologous tendon grafts to the bone: a histological and immunohistochemical of hamsting and patellar tendon grafts. Knee Surg Sports Trau- matol Arthrose, 2010, 8: 26-31.
  • 5Yamazaki S, Yasuda K, Tomita F, et al. The effect of graft tunnel diameter disparity on healing of the doubled flexor tendon graft within the bone tunnel in anterior cruciate re- construction. Trans OrthopRes Soc, 2009, 24: 932.
  • 6Weiler A, Hoffmann RF, Bail HJ, et al. Tendon healing in a bone tunnel. Part II: Histologic analysis after biodegradable interference fit fixation in a model of anterior cruciate liga- ment reconstruction in sheep. Arthroscopy, 2002, 18(2): 124-135.
  • 7Fu F. Anterior cruciate ligament injury: Pathophysiology and current therapeutic principles. Proceedings of the 66th Annual Meeting of the American Academy of Orthopaedic Surgeons, Anaheim, CA, 2009.
  • 8Robert H, Es-Sayeh J, Heymann D, et al. Hamstring inser- tion site healing after anterior cruciate ligament reconstruc- tion in patients with symptomatic hardware or repeat rup- ture: a histologic study in 12 patients. Arthroscopy, 2003, 19: 948-954.
  • 9Kernwein GA. A study of tendon implantation into bone. Gynecol Obstet, 1942, 75: 794-796.
  • 10Goradia VK. Tendon-healing in a bone tunnel. Arthroseopy, 2003, 19(1): 111.

二级参考文献21

  • 1何国础,钱不凡,杨庆铭,冯建民.膝关节镜内自体中1/3骨-髌韧带-骨重建前交叉韧带手术探讨[J].中华骨科杂志,1997,17(1):23-25. 被引量:44
  • 2何国础,中华骨科杂志,1997年,17卷,23页
  • 3Yamakado K, Kitaoka K, Yamada H. The influence of mechanical stress on graft healing in a bone tunnel. Arthroscopy 2002;18(9):82-90
  • 4Koski JA, Ibarra C, Rodeo SA. Tissue-engineered Ligament. Orthop Clin North Am 2000;31(3):437-452
  • 5Goradia VK, Rochat MC, Grana WA. Tendon-to-bone healing of a semi-tendinosus tendon autograft used for anterior cruciate ligament reconstruction in a sheep model. Am J Knee Surg 2000;13(3):143-151
  • 6Hunt P, Rehm O, Weiler A. Soft tissue graft interference fit fixation: observations on graft insertion site healing and tunnel remodeling 2 years after ACL reconstruction in sheep. Knee Surg Sports Traumatol Arthrosc 2006;14(12):1245-1251
  • 7Robert H, Es-Sayeh J, Heymann D. Hamstring insertion site healing after anterior cruciate ligament reconstruction in patients with symptomatic hardware or repeat rupture: a histologic study in 12 patients. Arthroscopy 2003;19(9):948-954
  • 8Youn I, Jones DG, Andrews PJ. Periosteal augmentation of a tendon graft improves tendon healing in the bone tunnel. Clin Orthop 2004;419: 223-231
  • 9Mihelic R, Pecina M, Jelic M. Bone morphogenetic protein-7 (osteogenic protein-1) promotes tendon graft integration in anterior cruciate ligament reconstruction in sheep. Am J Sports Med 2004;32(7):1619-1625
  • 10Yamazaki S, Yasuda K, Tomita F. The effect of transforming growth factor-beta1 on intraosseous healing of flexor tendon autograft replacement of anterior cruciate ligament in dogs. Arthroscopy 2005;21(9):1034-1041

共引文献15

同被引文献9

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部