黄石地区男性不育症患者支原体培养及药敏分析

Analysis of Mycoplasma Culture and Drug Sensitivity for Huangshi Male Patients with Infertility

为了解黄石地区男性不育症患者泌尿生殖系统支原体感染状况及其耐药性,采用支原体分离培养鉴定与药敏试验试剂盒,对男性不育患者精液进行支原体分离培养鉴定及药敏试验。结果为:108例男性不育患者支原体培养阳性42例,阳性率为38.9%,其中解脲支原体(uu)阳性32例,阳性率为29.6%;混合型支原体7例,阳性率为6.5%;人型支原体(mh)3例,阳性率为2.8%。对照组48例,其中解脲支原体3例,阳性率为6.2%,经统计学处理,x2=17.25,P<0.01,有显著性差异。支原体对药物敏感的为交沙霉素、强力霉素和美满霉素,耐药率较高的是环丙沙星、罗红霉素和氧氟沙星。支原体感染是男性不育的一个重要因素,在诊疗过程中应综合考虑本地区流行情况及药敏试验,合理选择抗生素。

Objective： to understand the status of male infertility patients with urogenital mycoplasma infection and its drug resislance. Method： separation mycoplasma culture identification and drug susceptibility test kit are adopted for male infertility patients＇ sperm separation for mycoplasma culture identification and drug sus- ceptibility test. Results：of the 108 eases of male infertility patients,there are 42 mycoplasma euhure positive cases,accounting for 38.9% ,32 ureaplasma mycoplasma （uu） positive cases accounting for 29.6% , and 7 mixed type mycoplasma cases, accounting for 6.5%. The person type mycoplasma （mh） was found in 3 pa- tients with a positive rate 2.8%. Among the 48 control group cases,there are 3 eases of ureaplasma mycoplas- ma, positive rate 6.2%. After statistics processing x2 = 17.25, P 〈 0.01, significant differences are observed. Conclusion ： Thedrug sensitivity of mycoplasma are josamycin, doxycycline and minocycline. Meanwhile, it has the highest rate of resistance to ciprofloxacin, ofloxacin and erythromycin. In conclusion mycoplasma infection is an important factor in male infertility. In the process of diagnosisand treatment, the epidemiological charac- teristics of the region and drug sensitive test must be taken into account comprehensively, so as to make a rea- sonable choice of antibiotics.