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490例妊娠梅毒母婴妊娠结局的病例对照研究 被引量:9

Clinical analysis of 490 pregnant women with syphilis:a case control study
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摘要 目的探讨妊娠梅毒临床特点及影响妊娠结局的因素。方法回顾性分析2010年1月1日~2012年12月30日我院经血清学检查确诊为妊娠梅毒490例孕产妇的临床资料。结果抗梅毒治疗组足月产率高于未治疗组(P<0.05);死胎死产及先天梅毒发生率,未治疗组高于治疗组(P<0.05)。结论妊娠梅毒发病率呈上升趋势,规范抗梅毒治疗能改善妊娠梅毒患者的妊娠结局和围生儿预后,是降低先天梅毒发生率的关键。 Objective To investigate the clinical characteristic and the perinatal outcomes of pregnant women with syphilis.Methods 490 pregnant women with syphilis and their children in our hospital during 2010~2012.The data were collected in a retrospective population-based longitudinal study.The pregnant outcomes,perinatal prognosis and congenital syphilis were analysed.Results A very significant difference of incidence was found between the treated group of syphilis in pregnant women and untreated group of term delivery(P0.05).The incidences of fetal death、stillbirth and congenital syphilis in group A were significantly lower than group B(P0.05).Conclusion Effective anti-syphilis therapy would be the key to improve the outcomes of pregnancy with syphilis,prognosis of neonates and reducing incidence of congenital syphilis.
出处 《四川医学》 CAS 2013年第7期963-965,共3页 Sichuan Medical Journal
关键词 妊娠梅毒 妊娠结局 围生儿预后 pregnant syphilis pregnancy outcome perinatal prognosis
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