电针联合耳针治疗2型糖尿病203例临床观察

Clinical Observation on Electro-Acupuncture Combined with Auricular Acupuncture for 203 Cases of Type 2 Diabetes

目的观察电针联合耳针治疗2型糖尿病的临床疗效及影响因素。方法收集203例2型糖尿病患者,采用电针联合耳针辨证治疗,1个月为1个疗程,共3个疗程。治疗前后检测空腹血糖(FBS)、血脂[总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白(LDL-C)]、空腹瘦素(FLP)、空腹胰岛素(FINS)、胰岛素敏感指数(ISI)、胰岛素抵抗指数(Homa-IR)、胰岛素分泌指数(Homa-β),并分析相关因素(证型、肥胖度、年龄、病程、病因诱因)对临床疗效的影响。结果治疗后患者FBS、TC、TG、LDL-C、FINS、Homa-IR、FLP较治疗前均明显下降(P<0.01),HDL-C、ISI和Homa-β明显回升(P<0.01)。证型对临床疗效无影响(P>0.05),而肥胖度、年龄、病程、病因诱因均影响疗效(P<0.01)。结论电针联合耳针辨证治疗能显著改善2型糖尿病患者的血糖、血脂及胰岛β细胞功能,其对轻度肥胖、年龄小、病程短的患者疗效好。

Objective To observe the efficacy and influencing factors of electro acupuncture （EA） combined with auricular acupuncture （AA） for type 2 diabetes. Methods Totally 203 cases of type 2 diabetes were given combo therapy of EA and AA. The fasting blood sugar （FBS）, total cholesterol （TC）, triglyceride （TG）, high-density lipoprotein cholesterol （HDL-C）, low-density lipoprotein cholesterol （LDL-C）, fasting leptin （FLP）, fasting insulin （FINS）, insulin sensitivity index （ISI） and homeostasis model assessment for insulin resistance （HOMA IR） and Q-cell function （HOMA-β） was observed before and after treatment. The relevant factors on the efficacy of EA such as patterns, obesity degree, age, duration, etiology and incentives were analyzed. Results After 3-month treatment, FBS, TC, TG, LDL, FINS, HOMA-IR and FLP significantly decreased （P〈0.01） but HDL, ISI and HOMA-β significantly increased （P〈0.01） in 203 patients. Three patterns had no impact on the efficacy （P〈0.05）. The obesity degree, age and duration affected the efficacy （P〈0.01）. Conclusion EA combined with AA can obviously improve blood sugar, blood lipid and β-cell function. It is effective for type 2 diabetes patients with mild obesity, younger age and short duration.