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卵巢miRNA的表达与功能研究进展 被引量：3

Advances in research of miRNA expression and function in the ovary
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摘要 MicroRNAs(miRNAs)是近年来发现的一类小的非编码RNA,主要通过转录后调控基因表达。miRNAs在一些肿瘤,如结直肠、前列腺、人卵巢组织和细胞中的表达水平变化及其抑制肿瘤细胞增殖的功能是研究的热点之一,本文综述了miRNA在卵巢中的表达特点及可能的功能。 MicroRNAs （miRNAs） , as small non-coding RNAs, have been found to regulate gene expression at the post-transcrlptional levels. Many studies on miRNAs are mainly focused on cancers such as human colorectal, prostate and ovarian cancers because miRNAs expression has been found to be changed in cancer tissues and negatively regulate the ceil proliferation. This review focuses on recent findings on the miRNA expression and function in the ovary.
作者 张建芳 张水文 李建华 郭军红 徐野
机构地区 北京军区总医院生殖医学中心
出处 《中国比较医学杂志》 CAS 2013年第8期67-71,79,共6页 Chinese Journal of Comparative Medicine
关键词 MICRORNAS 卵巢 颗粒细胞 激素 MicroRNAs Ovary Granulosa cells Hormone
分类号 R33 [医药卫生—人体生理学] R33 [医药卫生—人体生理学]
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参考文献40

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二级参考文献11

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共引文献18

同被引文献40

引证文献3

二级引证文献7

中国比较医学杂志
2013年 第8期

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