肝动脉化疗栓塞联合射频消融术治疗原发性大肝癌的临床观察

Clinical observation on hepatic arterial chemotherapy embolization combined with radio frequency ablation in treating large liver cancer

目的分析采用肝动脉化疗栓塞联合射频消融方法对治疗原发性大肝癌的具体临床作用。方法选择2010年8月～2011年9月在我院治疗的54例原发性大肝癌患者作为研究对象,并对治疗后效果进行跟踪。首先使用动脉化疗栓塞法治疗,治疗次数是2～3次;再给予射频消融治疗2～4周。手术后跟踪观察患者的各种临床表现及复发情况等。结果比较手术前后患者情况,手术后54例患者的各种症状有所缓解。甲胎蛋白下降的患者有45例,没发生变化的有3例,升高的有6例。所有病例的平均生存时间是13个月。结论肝动脉化疗栓塞联合射频消融术在治疗不可切除的原发性大肝癌中具有明显的作用,详细结论还需进一步验证。

Objective To analyze the clinica effects of hepatic arterial chemotherapy embolization （TACE） combining with radio therapy ablation （RFA） on the large primary hepatocellular carcinoma （HCC）. Methods TACE on 54 cases of large HCC patients hospialized in our hospital from Aug 2010 to September 2011 was performed for 2-3 times, and then RFA was pertormed for 2-4 weeks. The clinical recurrence situation was followed up. Results The clinical symptoms of the 54 cases were relieved. AFP value of 45 cases was decreased. 3 cases was no change and 6 cases increased. The averge survival duration was 13 months. Conclusion TACE combined with RFA has obvous effect on the large HCC that has no chance for surgery. Details still need to be further investigation.