彩色多普勒筛查早中期胎儿畸形的临床意义

Clinial significance of color Dopper ultrasound on fetal malformation screening in the early or mid trimester of pregnancy

目的探讨彩色多普勒筛查在早中孕期胎儿(孕11～14周)畸形的临床意义。方法回顾性分析我院2年间6058例早中孕期孕妇(孕11～14周)彩色多普勒检查,经本院引产病理证实52例严重胎儿畸形病例。结果经本院引产病理证实的严重胎儿畸形52例(包括6例双胎畸形)。单纯NT≥3mm合并严重胎儿畸形31例,NT<3mm合并严重胎儿畸形15例。结论彩色多普勒筛查早中孕期胎儿畸形有较大的临床意义,值得早中孕期常规筛查应用推广。

[Abstract] Objective To investigate the clinical significance of color Doppler ultrasound on fetal malformation screening in the early or mid trimester of pregnancy. Methods A retropective analysis in a total of 6058 cases of fetus between 11 and 14 gestational weeks was perforned in 52 cases, which had been diagnosed to be fetal malformation by ultrasound in our hospital from 2010 to 2011, and those cases had been confirmed by induced labor or post partum. Results There had been 52 confiemed cases of fetal serious malformation demonstrated by pathology, including 6 cases of conjoint twins, 31 cases that NT was over or equal to 3 mm and fetals serious malformation, 15 cases that NT was less than 3 mm and fetals serious malformation. Conclusion Color Doppler ultrasound on fetal malformation screening in the early or mid trimester of pregnancy had great clinical significance to decrease neonatal malformation and to improve life quality. It is worthy to be promoted/popularized.