微波辅助合成羟基磷灰石研究

Research of Microwave-assisted Synthesis of Hydroxyapatite

羟基磷灰石由于具有良好的生物相容性和生物活性而应用广泛。本文分别以Ca(NO3)2·4H2O、(NH4)2HPO4·3H2O为Ca源和P源,采用微波辅助加热的方式合成羟基磷灰石。使用傅里叶红外光谱(FT-IR)、X-射线衍射(XRD)和扫描电镜(SEM)对获得的产物进行了表征。分别研究了微波反应时间、反应功率和原料Ca/P比对合成羟基磷灰石形貌和结晶度的影响。结果表明,不同条件下,产物的形貌与结晶度均有不同。当合成时间为5 min,微波功率为400 W,Ca/P比为2.0时,产物为具有结晶良好的羟基磷灰石。

Hydroxyapatite （HAP） has been reported to be widely used because of good biocompatibility and bioactivity. In this current paper, HAP samples were prepared by a microwave hydrothermal method using Ca（NO3）2·4H2O、（NH4）2HPO4·3H2O as the raw materials. The obtained samples were characterized with a series of method including Fourier transform infrared spectrometry （ FT-IR）, X-ray diffraction （XRD） and scanning electron microscope （SEM）. The results demonstrated that the microwave reaction time, reactive power and Ca/P mole ratios have influence to morphologies of the synthetic HAP particles, and the product has the best of crystallinity with the conditions of 5 min reactive time, 400 W reactive power and the Ca/P ratio of 2.0.