阿奇霉素联合红霉素治疗小儿支原体肺炎的疗效观察

Efficacy observtion of azithromycin combined with erythromycin in treatment of the mycoplasma pneumonia in children

目的探讨阿奇霉素联合红霉素治疗小儿支原体肺炎的临床效果。方法将98例支原体肺炎患儿随机分为两组,对照组49例采用阿奇霉素治疗,观察组49例则在对照组的基础上加用红霉素治疗,并比较两组的临床疗效。结果观察组总有效率为97.96%,对照组为81.63%,两组相比较差异有统计学意义(P<0.05),观察组患儿的退热时间、咳嗽消失时间、肺部啰音消失时间、平均住院时间均少于对照组(均P<0.05)。结论阿奇霉素联合红霉素治疗小儿支原体肺炎疗效显著、安全、可靠、减少了住院时间,提高了患儿的生存质量。

Objective To explore theclinicaleffectof the azithromycin combined with erythromycininthetreatmentof the mycoplasma pneumonia in children.Methods 98 children withmycoplasma pneumoniawere randomlydivided into two groups,patients（n = 49） in the control group were treated withazithromycin,while the other 49children（observation group） were treated with erythromycinand azithromycin,and then compare theclinical efficacy of both groups.Results The total effective rateofthe observation group was 97.96%,while thecontrolgroup was 81.63%,the difference between tow groups wasstatistically significant（P〈0.05）.The time cost in bring down the fever,cough disappeared,pulmonary ralesdisappeared andaverage time spent in hospital wereless thantheseofthecontrolgroup（P〈0.05）.Conclusions Azithromycin combined with erythromycinis more effective,safety,reliability in the treatmentofmycoplasma pneumonia in children for it could reducehospitalizationtime and improve life quality of children.