柴胡疏肝散加减治疗脑卒中后抑郁40例疗效观察

Observetion of the curative effect of radix bupleuri liver powder in the treatment of depression after cerebral apoplexy for 40 cases

目的观察柴胡疏肝散加减治疗脑卒中后抑郁的临床疗效。方法将80例患者随机分成两组,对照组40例常规服用氟哌塞顿美利曲辛,治疗组40例加服柴胡疏肝散加减中药汤剂,在治疗前和治疗8周后行汉密尔顿抑郁量表(HAMD)及神经功能缺损评分(CNS)评定其疗效。结果治疗组总有效率明显高于对照组,两组间比较差异有显著意义(P<0.05);治疗组减分率明显高于对照组,两组间比较差异有显著意义(P<0.05);两组治疗前与治疗后评分降低,治疗前后比较差异有显著意义(P<0.05)。结论柴胡疏肝散加减治疗脑卒中后抑郁有显著疗效。

Objective To observe the clinical curative effect of radix bupleuri liver powderin treatment of depression after stroke.Methods Patients（n = 80） were randomly divided into control group and treatment group,40 cases each.Patients in control group were treated withDroperidol Seton melitracen,while the treatment group treated with Droperidol Seton melitracenand radix bupleuri liver powder.We assess their depression and neuro function before treament and 8 weeks later.Results The total effective rate of treatment group was significantly higher than that of control group（P〈0.05）;The score of treatment group was lower than that of control group（P〈0.05）;The score of both groups were significantlydecreased because of the treat（P〈0.05）.Conclusions Radix bupleuri liver powder has a significant curative effect on depression after cerebral apoplexy.