摘要
目的 检测孕妇静脉血、脐血中胰岛素样生长因子－Ⅰ (IGF－Ⅰ )及胰岛素样生长因子结合蛋白-3(IGFBP-3)水平，探讨 IGF－Ⅰ、 IGFBP-3与胎儿宫内发育的关系。方法 采用美国 DSL公司试剂盒。总计 81例孕妇，其中正常孕妇 38例，妊娠糖尿病孕妇 20例，正常妊娠分娩巨大儿孕妇 23例，采用放射免疫方法测定。 结果 正常组及巨大儿组孕妇静脉血 IGF-I与新生儿体重呈正相关 (r=0.653， r=0.640，两组 P均
To study the relations between IGF-I、 IGFBP-3 and human fetal growth. Methods The blood samples of maternal serum (MS) and umbilical cord serum(UCS) from 81 cases with singleton term pregnancy including 38 cases of normal pregnancy (NP), 20 cases of gestational diabetic mellitus (GDM), 23 cases of macrosomia of non-diabetic pregnancy (MNDP) were examined for IGF－Ⅰ and IGFBP-3 levels by immunoassay kit from DSL, USA . Results IGF-I in MS of NP and MNDP showed a positive correlation with birth weight (BW) ( r=0.653 and r= 0.640 respectively , both P
出处
《中国医学科学院学报》
CSCD
北大核心
2000年第5期476-478,共3页
Acta Academiae Medicinae Sinicae
关键词
IGF-I
胎儿宫内发育
IGFBP-3
insulin-like growth factor-I (IGF-I)
fetal development
insulin-like growth factor binding protein
-3(IGFBP-3)
