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抗凝治疗与脑出血的相关性研究 被引量:2

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摘要 目的探讨抗凝治疗与脑出血患者的出血量及预后的相关性。方法回顾性分析神经抢救中心2002年1月至2012年12月收治的235例自发脑出血患者的临床资料。将使用华法令抗凝治疗的用药组患者与未用药组患者临床资料进行对比分析。结果用药组患者平均年龄72岁,显著大于非用药组66岁(P<0.05)。在血管性危险因素中用药组患者中合并冠心病的比例显著多于与未用药组(P<0.05)。用药组患者的平均出血量为51.7 ml,显著多于未用药组的26.2 ml。患者的死亡率与患者INR值和脑出血量存在正相关性。结论抗凝治疗及抗凝强度与抗凝并发脑出血患者预后存在相关性。
出处 《河北医药》 CAS 2013年第15期2274-2275,共2页 Hebei Medical Journal
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  • 1Hart RG,Tonarelli SB,Pearce LA.Avoiding central nervous system bleeding during antithrombotic therapy:recent data and ideas.Stroke,2005,36:1588-1593.
  • 2Flibotte JJ,Hagan N,O'Donnell J,et al.Warfarin,hematoma expansion,and outcome of intracerebral hemorrhage.Neurology,2004,63:1059-1064.
  • 3Nicolini A,Ghirarduzzi A,Iorio A,et al.Intracranial bleeding:epidemiology and relationships with antithrombotic treatment in 241 cerebral hemorrhages in Reggio Emilia.Haematologica,2002,87:948-956.
  • 4Tran H,Anand SS.Oral antiplatelet therapy in cerebrovascular disease,coronary artery disease and peripheral arterial disease.The Journal of the American Medical Association,2004,292:1867-1874.
  • 5Sjoblom L,Hardemark HG,Lindgren A,et al.Management and prognostic features of intracerebral hemorrhage during anticoagulant therapy:a Swedish multicenter study.Stroke,2001,32:2567-2574.
  • 6Flibotte JJ,Hagan N,O'Donnell J,et al.Warfarin,hematoma expansion,and outcome of intracerebral hemorrhage.Neurology,2004,63:1059-1064.
  • 7Cucchiara B,Messe S,Sansing L,et al.Hematoma growth in oral anticoagulant related intracerebral hemorrhage.Stroke,2008,39:2993-2996.
  • 8Nilsson OG,Lindgren A,Brandt L,et al.Prediction of death in patients with primary intracerebral hemorrhage:a prospective study of a defined population.J Neurosurg,2002,97:531-536.
  • 9Flaherty ML,Kissela B,Woo D,et al.The increasing incidence of anticoagulant-associated intracerebral hemorrhage.Neurology,2007,68:116-121.
  • 10Flaherty ML,Tao H,Haverbusch M,et al.Warfarin use leads to larger intracerebral hematomas.Neurology,2008,71:1084-1089.

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