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左卡尼汀对维持性血液透析患者左心室肥厚和心功能的影响 被引量:7

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摘要 慢性。肾脏疾病(CKD)是一种累及多个系统和器官的损害性疾病,其中心血管并发症(CVD)是其最常见的,在终末期肾衰患者中发生CVD的危险性是普通人群的50倍,发生率高达75%,其中左心室肥厚(LVH)占81.6%[1]。50%以上的血液透析患者死于心血管疾病,部分患者长期存在慢性心功能不全(CHF)。逆转心肌重构则是改善患者CHF的机制之一。左卡尼汀又称左旋肉碱,具有多种生理生化功能,可以改善透析患者的并发症。我们观察了左旋卡尼汀对78例维持性血液透析患者左心室肥厚和心功能的影响,现报告如下。
出处 《河北医药》 CAS 2013年第16期2483-2484,共2页 Hebei Medical Journal
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