老年心血管疾病与骨质疏松的关系

Study on the relationship between the elderly cardiovascular disease and osteoporosis

目的探讨心血管疾病（cardiovascular disease,CVD）与骨质疏松（osteoporosis,OP）的关系。方法收集100例正常体检者（对照组）和97例心血管疾病患者（CVD组）的临床资料。CVD组中冠心病患者45例,高血压患者36例。经X线骨密度测定仪测定左股骨颈、L2~L4椎体的骨密度（bone mineral density,BMD）,比较两组骨密度的变化。结果 CVD组BMD较对照组降低,CVD组冠心病患者L2~L4椎体的BMD较对照组降低,而两组左股骨颈BMD差异无统计学意义;与对照组相比,CVD组高血压患者L2~L4椎体、左股骨颈BMD差异均无统计学意义（P〉0.05）。结论 CVD与OP存在一定的关系;冠心病与L2~L4椎体BMD关联,可通过行L2~L4椎体BMD测定评估两者的疾病风险。

Objective To study the relationship between elderly cardiovascular disease and osteoporosis.Methods 97cases（CVD patients group）and 100cases（normal control group）with completed clinical data were collected.The dural-energy X-ray absorptiometry scanner was applied to measure the bone mineral density（BMD）of lumbar L2-L4vertebrae and the left femoralhead.Results Compared with BMD of normal control group,BMD of CVD patients were obviously decreased（P＆lt;0.05）;the BMD of lumbar L2-L4vertebrae of coronary heart disease patients were obviously decreased（P ＆lt;0.05）;however there were no significantly differences in hypertension patients（P ＆gt;0.05）.Conclusion Cardiovascular disease was related to osteoporosis,especially BMD of lumbar L2-L4vertebrae with coronary heart disease.