新诊断中青年2型糖尿病患者合并高血压的动态血压分析被引量：3

Analysis of 24h ambulatory blood pressure monitoring in new diagnostic young and middle-aged diabetic patients with primary hypertension

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摘要目的观察新诊断中青年2型糖尿病患者合并原发性高血压24 h动态血压(ABPM)的变化及其临床特点。方法对106例新诊断的中青年2型糖尿病合并原发性高血压患者(A组)行ABPM检查,分析其可能的变化及其临床特点,另设106例单纯的中青年原发性高血压患者(B组)作为对照。结果 A组白天平均收缩压(平均为162±18 mmHg)高于B组(平均为148±12 mmHg)(P<0.05);A组白天和夜间SBP分别(42±26)%和(74±38)%,白天和夜间DBP负荷分别为(10±12)%和(12±14)%,B组白天和夜间SBP分别(28±25)%和(40±34)%,白天和夜间DBP负荷分别为(6±9)%和(9±10)%,A组白天和夜间SBP及DBP负荷明显高于B组(P<0.01);A组SBP及DBP负荷昼夜差值明显低于B组(P<0.01);A组异常血压形态(非杓形)及节律消失者为62%和89%,而B组为36%和57%,A组血压形态非杓形及节律消失者明显高于B组(P<0.01)。结论新诊断中青年2型糖尿病患者合并原发性高血压者收缩压较高,血压负荷值增高,而ABPM昼夜节律消失和异常血压形态比例明显增高。 Objective To observe the changes and its clinic characterestics of 24h ambulatory blood pressure monitoring（ABPM） in new diagnostic young and middle-aged diabetic patients with primary hypertension.Methods One hundred and six new diagnostic young and middle-aged diabetic patients with primary hypertension（group A） were examined using ABPM,meanwhile its possible changes and clinical characteristics were analyzed.One hundred and six young and middle-aged patients with primary hypertension（group B） were as control group.Results The daytime mean systolic blood pressure（SBP） in group A（162 ± 18 mmHg） was higher than that in group B（148 ± 12mmHg,P0.05）.The daytime and night SBP in group A were 42%±26% and 74%±38%,while in group B were（28±25）% and（40±34）%.The daytime and night DBP in group A were 10%±12% and 12%±14%,while in group B were 6%±9% and 9%±10%.The daytime and night SBP and DBP load in group A were obviously higher than those in group B,while daytime and night SBP and DBP load differences in group A were obviously lower than those in group B（P0.01）.The percent of abnormal blood pressure form（non-scoop shape） and rhythm disappear in group A were 62% and 89%,which were significantly higher than in group B（36% and 57%,P0.01）.Conclusion The new diagnostic young and middle-aged diabetic patients with primary hypertension have higher systolic blood pressure and blood pressure load value,meanwhile,the probability of ABPM diurnal rhythm disappear and abnormal blood pressure form are increased obviously.

作者唐文军雷涛

机构地区同济大学附属同济医院心功能室同济大学附属同济医院内分泌科

出处《同济大学学报（医学版）》 CAS 2013年第3期109-112,共4页 Journal of Tongji University(Medical Science)

基金上海市卫生局科研基金(20124256)

关键词糖尿病原发性高血压动态血压 diabetes mellitus primary hypertension ambulatory blood pressure monitoring

分类号 R543 [医药卫生—心血管疾病]

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参考文献9

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