摘要
HIV慢性感染是全球性的问题和大家关注的热点,其主要标志是CD4+T淋巴细胞计数的减少和免疫系统的功能失调。关于其发病机制方面的研究很多,但是关于B细胞方面的研究较少,而且关于其在HIV慢性感染中的功能和意义尚不清楚。本文对HIV-1慢性感染者B细胞功能受损的临床意义进行综述,以期为HIV感染的研究工作提供参考。
Chronic H1V iniection is a global question and an issue iocused on by many researchers. The major characteristics of chronic HIV infection are the decrease in CD4＋ T lymphocyte counts and the dysfunction of immune system. Many studies have been carried out on the pathogenesis of HIV infection, but only a few studies on B cells in patients with chronic HIV infection. Moreover, the function and significance of B cells in chronic HIV infection remain unknown. The authors summarize the clinical significance of B cell dysfunction in patients with chronic HIV-1 infection, intending to provide a reference for the studies on HIV infection.
出处
《传染病信息》
2013年第4期243-246,共4页
Infectious Disease Information
基金
国家"十二五"科技重大专项(2012ZX10001-006-003003)
国家优秀青年基金(81222024)
