摘要
目的评价不同病因甲状腺功能亢进症(甲亢)的核素显像特征,观察131I治疗后甲状腺显像的变化。方法收集402例甲亢患者,于131I治疗前进行甲状腺显像,诊断甲亢病因;于131I治疗后6个月后再次进行甲状腺显像,比较治疗前后显像的变化。结果根据甲状腺显像结果,402例患者中,格雷夫斯病351例(351/402,87.31%),包括弥漫性甲状腺肿185例,结节性甲状腺肿166例;甲状腺自主性高功能腺瘤(TA)42例(42/402,10.45%);多结节性甲状腺肿伴甲亢(TMNG)9例(9/402,2.24%)。131I治疗后甲状腺显像:格雷夫斯病弥漫增生组织均匀缩小;TA热结节转变为冷结节,周围和对侧组织显影恢复;TMNG原多发小热结节多缩小或消失,原受抑甲状腺组织内出现新的多发小热结节。结论不同病因甲亢的甲状腺核素显像具有不同特征;131I治疗后甲状腺显像变化明显。
Objective To observe the manifestations of thyroid radionuclide imaging in hyperthyroidism induced by differ- ent causes and the changes of imaging after radioiodine 131（131I） treatment. Method Totally 402 patients with hyperthy- roidism underwent thyroid radionuclide imaging to diagnose the cause of disease before 131I therapy. Changes of thyroid ra- dionuclide imaging were observed 6 months after 131I therapy and was compared with those before therapy. Results Ac cording to the thyroid radionuclide imaging, there were 351 cases （351/402, 87.31% ） of Graves disease, including 185 dif fuse goiter and 166 nodular goiter, 42 cases （42/402, 10.45%） of solitary toxic adenoma （TA） and 9 cases （9/402, 2.24%） of toxic muhinodular goitre （TMNG）. After 131I therapy, diffuse hyperplasia of thyroid tissue lessened in Graves disease, the hot nodule was converted into cold nodule and the developments of surrounding, while contralateral tissues were recovered in TA, multiple hot nodules on original location lessened or disappeared and occurred in former inhibited tis- sues in TMNG. Conclusion Hyperthyroidism induced by different causes shows different characteristics in thyroid nuclide imaging. There are significant changes of imaging before and after treatment with 131I.
出处
《中国医学影像技术》
CSCD
北大核心
2013年第9期1442-1445,共4页
Chinese Journal of Medical Imaging Technology
