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维生素D、自噬与多发性硬化

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摘要 多发性硬化（multiple sclerosis,MS）是导致青年人残疾的最常见中枢神经系统（central nervous system,CNS）疾病.目前认为MS是一种确切病因尚不清楚的以CNS脱髓鞘为主要病理损害的器官特异性自身免疫性疾病,遗传易患性以及环境因素共同参与了MS的发病过程.维生素D缺乏、某些特殊病原体如EB病毒感染、吸烟等是目前较为认可的与MS发病风险相关的环境因素[1].维生素D缺乏容易干预,对MS的预防和治疗具有重要的研究和应用价值.
作者 卢婷婷 陆正齐
机构地区 中山大学附属第三医院神经病学科
出处 《中华神经科杂志》 CAS CSCD 北大核心 2013年第9期622-625,共4页 Chinese Journal of Neurology
关键词 维生素D缺乏 多发性硬化 特异性自身免疫性疾病 自噬 中枢神经系统 EB病毒感染 环境因素 遗传易患性
分类号 R725.914.4 [医药卫生—儿科]
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参考文献31

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二级参考文献15

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中华神经科杂志
2013年 第9期

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