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去整合素-金属蛋白酶17在胶质瘤侵袭转移中的作用机制 被引量：5

Upregulation of ADAM17 gene expression contributes to aggressive behavior of glioma cells
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摘要 胶质瘤是最常见的原发性中枢神经系统恶性肿瘤，多呈浸润性生长．与正常脑组织之间无明显界限，目前的治疗效果不理想。其中，肿瘤细胞高度侵袭是胶质瘤高复发、高死亡率的主要原因，同时也是胶质瘤发生、发展进程中重要的生物学标志，与胶质瘤患者的预后密切相关。围绕着肿瘤侵袭机制的研究一直以来就是胶质瘤研究的重点。
作者 陈祥荣 王向宇
机构地区 南方医科大学珠江医院神经外科 福建医科大学附属第二医院神经外科
出处 《中华神经医学杂志》 CAS CSCD 北大核心 2013年第9期960-962,共3页 Chinese Journal of Neuromedicine
关键词 去整合素-金属蛋白酶17 神经胶质瘤 侵袭机制 Disintegrin and metalloprotease 17 Glioma Invasiveness
分类号 R739.4 [医药卫生—肿瘤]
  • 相关文献

参考文献33

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二级参考文献18

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共引文献7

同被引文献30

  • 1杨甫德,陈彦芳.中国失眠防治指南[M].北京:人民卫生出版社,2012:3.32.
  • 2张艳,张雪鹏,吕捷,等.去整合素2金属蛋白酶17与肿瘤的研究进展[J].肿瘤学杂志,2013,17(2):208-211.
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引证文献5

二级引证文献11

中华神经医学杂志
2013年 第9期

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