射频靶点结合胶原酶治疗颈椎间盘突出症研究

Treatment of Cervical Intervertebral Disc Herniation by Radio Frequency Target Combined with Collagenase

目的观察颈椎间盘靶点射频消融术结合胶原酶治疗的疗效．方法将2011年3～9月收治的40例颈椎间盘突出患者分2组，A组20例使用颈椎间盘靶点射频消融治疗，B组20例行颈椎间盘靶点射频消融术结合胶原酶治疗颈椎间盘突出症．结果40例患者术后1周，6个月后使用VAS评分对比术前VAS评分差值行t检验．术后1周2组对比差异无统计学意义；术后6个月检测结果B组与A组比较有统计学意义（P〈0．05）．结论颈椎间盘靶点射频消融结合胶原酶治疗颈椎病可以有效改善患者疼痛症状，且近期及远期治疗效果均可，远期疗效与单纯颈椎间盘靶点射频消融治疗差异有统计学意义，颈椎间盘射频消融术结合胶原酶治疗更为安全、副作用小、风险小、近期与远期疗效均可，值得推广．

Objective To observe the treatment effect of radio frequency target combined with collagenase in treatment of cervical intervertebral disc herniation. Methods From March 2011 to September 2011, 40 patients with cervical intervertebral disc herniation were divided into 2 groups： Group A and Group B. Patients in Group A were given radio frequency target radiofrequency for treatment of the cervical intervertebral disc herniation and patients in Group B of 20 were given radio frequency target combined with col｜agenase for treatment of cervical intervertebral disc herniation. Results 40 patients were followed up for 6 months. At the 1st week and 6 months after surgery, the VAS score difference between before and after surgery in patients were compared between two groups by t test. There was no statistically significant difference at the 1st week after surgery between two groups （P 〉 0.05） , while 6 months after surgery, there was statistically significant difference between two groups （P 〈 0.05） Conclusion Radio frequency target combined with collagenase for treatment of cervical intervertebral disc herniation can alleviate the pain symptoms of patients, and the short-term and long-term curative effect is very good. The long-term curative effect has statistically significant difference with pure target radiofrequency ablation treatment. Radio frequency target combined with collagenase for treatment of cervical intervertebral disc herniation has good safety, few side effects, low risks and good short-term and long-term curative effect, so it deserves to be generalized.