法洛四联症的MRI诊断及评估

The MRI diagnosis and evulation of tetralogy of Fallot

目的通过回顾性分析法洛四联症(tetralogy of Fallot,TOF)的MRI表现,探讨法洛四联症的MRI诊断及评估价值。方法回顾性分析15例经手术证实的法洛四联症资料,并收集20例正常志愿者作为对照组。分析法洛四联症的MRI表现,并对比法洛四联症组与正常组之间的心脏大血管结构改变特点。结果 15例TOF患者中,均可见室间隔缺损,右室流出道和肺动脉狭窄,右室肥厚及主动脉骑跨。TOF右室流出道组内径(9.47±2.80)mm较正常组(17.75±2.31)mm明显变窄,TOF组的右心室游离壁的厚度(11.67±2.77)mm较正常组(3.50±0.83)mm明显增厚,TOF组的左右室壁厚度比平均约为0.86,明显低于正常组的2.87,TOF组的主动脉根部(35.93±6.68)mm及升主动脉内径(35.13±6.89)mm较正常组(28.60±3.64)mm、(27.61±3.95)mm增大,均P<0.05,主动脉骑跨率平均约为50.47%。结论 MRI不仅可以准确的诊断TOF,也可以对右室流出道,右心室肥厚及升主动脉做相应的评估。

Objective To investigate the value of diagnosis and evaluation of MRI in tetralogy of Fallot （TOF） through retrospectively analyzing the MRI manifestation of TOF. Methods We collected 15 cases of TOF that proved by operation and 20 normal volunteers as references. We summarized the MRI manifestation of TOF, and songht the differences be tween TOF group and normal group. Results Ventricle defect, right outflow tract or pulmonary stenosis, right ventricle hypertrophy and aorta overriding were revealed well through MRI. The right outflow tract diameter was （9.47 ± 2.80） mm, narrower than normal group （17.75±2.31） mm, the thickness （11.67±2.77） mm of the free wall of the right ven- tricle was thicker than normal group （3.50±0.83） mm, the ratio of left ventricle wall thickness （0.86） to left ventricle wall thickness was bigger than normal group （2.87）, the aorta root and ascending aorta diameter was bigger than normal group, the differences were all signifant. The average ratio of aorta overriding was about 50.47%. Conclusion Not only diagnosing TOF accurately, MRI also had the value of evaluating right outflow tract, right ventricle hypertrophy and as- cending aorta.