摘要FOXM1(Forkhead box protein M1)是调控细胞增殖的重要转录因子,参与调控肿瘤细胞的增殖、凋亡、浸润与转移等。近年来研究发现它在卵巢癌中存在过高表达并对卵巢癌的发生、发展及预后起着重要的作用,提示FOXM1有望成为新的肿瘤标志物,作为卵巢癌早期诊断、预后指标和治疗的新靶点。
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