成人斜视生存质量评估量表在中国人群的应用

Utilization of the adult strabismus questionnaire （AS-20） in China

目的制作一个评价中国成人斜视患者生存质量状况的评估量表，探讨其应用在中国成人斜视患者时的信度和效度。方法前瞧性病例对照研究。将英文版的成人斜视生存质量量表（AS-20）翻译为rlt文．矸集就诊的成人斜视患者102例和视功能正常的对照肯102例。对这2组患者使用中文版的成人斜视生存质量评估量表进行问卷调查。分析量表的内在一致性、重测信度、内容效度、结构效度和判别效度，同时分析影响患者CAS-20得分的相关冈素。汁箅克朗巴赫仪系数和岗子分析评估量表信度和效度，Spearman’s序列相天性分析评估条目集合效度和分辨效度。结果CAS-20分为社会心理维度（条目1-10）和视功能维度（条目11-20）。经102例成人斜视患者和102视功能正常的对照者检验，总量表、利：会心理维度和}见功能维度的克朗巴赫系数分别为0．846、0．819、0．883，分半信度为0．846、0．801、0．898，重测信度为O．811、0．862、0．723．因子分析提取出6个公凶子，能归纳为社会心理维度和况功能维度2个维度．斜视患肯的得分显著低于正常对照组得分．伴有复视的斜视患并得分比没有复视的患者得分更低。、量表得分与患者年龄、性别、视力水平及眼位偏斜方向无明届相关性。结论中文版AS-20具有良好的信度和效度，能敏感反映中国成人患者与斜视相芙的生存质量的变化。

Objective A Chinese version of the Adult Strabisnms-20 （CAS-20） was developed by translating the AS-20 into Chinese, and its reliability and validity were evaluated on adult strabismus patients in China. Methods This was a prospective case-control study. One hundred and two adults with strabismus and 102 visually healthy aduh controls were recruited to answer the 5-level Likert items of the CAS-20. Age and gender, as well as the clinical data of the recruited subjects were documented. Internal consistency, test-retest reliability, correlations between items and their respective subscales, and format validity were evaluated to assess the reliability and validity of the questionnaire. Cronbach＇s c~ coefficients were used to test the internal consistency of the questionnaire. The internal consistency of the items and lhe validity of item discrimination were evaluated by Spearman＇s rank correlation. VARIMAX rotation factor analysis was used to estimate the validity of the format . Results The number of responses for each item was calculated, as well as the individual item＇s correlation with its respective subscales. Cronbach＇s c~ coefficient （0.846, 0.819, 0.883） and split-half coefficient （0.846, 0.801, 0.898） for the 2 subscales and the CAS-20 were satisfactory. The intraclass correlations＇ coefficient for test-retest reliability was 0.723-0.862. Patients with strabismus had signifieantly lower scores on the CAS-20 than the controls. Factor analysis identified 6 principal factors that could be grouped into 2 subscales. The results supported the validity of the CAS-20 format. Conclusion The CAS-20 presented satisfactory reliability and validity in this study. It is suggested that the questionnaire can be applied in clinical trials or research on adult Chinese strabismus patients.