口服轮状病毒活疫苗在社区防疫中的应用价值分析

Application Value of Vaccine live Oral rotavirus in Epidemic Prevention in the Community

目的分析口服轮状病毒活疫苗在社区防疫中的应用价值。方法回顾性分析在我社区就诊的轮状病毒性腹泻患儿128例,将其随机分成观察组和对照组,观察组口服轮状病毒活疫苗,对照组未口服轮状病毒活疫菌对于其它疫苗的接种两组均相同。随访半年,观察两组患儿的平均患病时间和发病情况等。结果观察组腹泻8例(12.5%),住院3例(4.7%),平均患病时间(4.2±1.2)天;对照组腹泻20例(31.3%),住院9例(14.1%),平均患病时间(7.6±2.1)天。两组患儿的结果均具有统计学差异(P<0.05)。结论在预防儿童轮状病毒腹泻上,口服轮状病毒活疫苗具有良好的效果,建议在临床上推广使用,从而为临床治疗提供一定的依据。

Objective Application value of live orat rotavirus vaccine in prevention in the community. Methods Retrospective analysis in our community treatment of rotavirus diarrhea in 128 cases, they were randomly divided into the observation group and the control group, the observation group live oral rotavirus vaccine, the control group did not live oral rotavirus vaccine for other vaccination two groups are the same. Follow-up for half a year, two groups were observed in children with a mean duration of disease and the morbidity of etc. Results The observation group 8 cases of diarrhea （12.5%）, 3 cases（4.7%）, the average time （4.2±1.2） days; the control group 20 cases of diarrhea （31.3%）, 9 cases（14.1%）, the average time （7.6±2.1） days. There was significant statistical difference between the two groups （P〈 0.05） results. Conclusion In the prevention of rotavirus diarrhea in children, two live oral rotavirus vaccines has a good effect, recommended to use in clinical practice, so as to provide some references for clinical treatment.