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冠心病患者血清apoA5水平的临床价值

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摘要 载脂蛋白A5（apolipoprotein A5．apoA5）是由两个独立的研究小组于2001年通过比较小鼠与人的基因组DNA同时发现的一种新的载脂蛋白。
作者 朱立岳 胡雷光 惠志强 王昕蕾
机构地区 上海市静安区中心医院复旦大学附属华山医院静安分院检验科
出处 《实用检验医师杂志》 2013年第2期112-113,127,共3页 Chinese Journal of Clinical Pathologist
关键词 冠心病患者 临床价值 载脂蛋白A 血清 基因组DNA 水
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献18

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  • 2Pennacchio LA, Rubin EM. Genomic strategies to identify mammalian regulatory sequences. Nat Rev Genet, 2001,2:100-109.
  • 3李溪,姚成立.载脂蛋白A5基因的研究进展[J].宁夏医学杂志,2008,30(4):380-381. 被引量：1
  • 4Pennacchio LA, Olivier M, Hubacek JA, et al. An apolipoprotien in- fluencing triglycerides in humans and mice revealed by comparative sequencing. Science, 2001,294 : 169-173.
  • 5胡雷光,朱立岳,陈坚,王昕蕾,楚青.载脂蛋白A5基因-3A/G多态性对血脂代谢及其相关疾病的关系探讨[J].检验医学,2011,26(9):593-597. 被引量：4
  • 6Yin RX, Li YY, Wu JZ, et al. Interactions between the apolipopro- tein al/c3/a5 haplotypes and alcohol consumption on serum lipid lev- els. Alcohol Clin Exp Res, 2013,37 :234-243.
  • 7Yin RX, Li YY, Lai CQ. Apolipoprotein AI/C3/A5 haplotypes and serum lipid levels. Lipids Health Dis,2011,10: 140.
  • 8Guardiola M, Ribaha J, G6mez-Coronado D, et al. The apolipopro- tein A5 (APOA5) gene predisposes Caucasian children to elevated triglycerides and vitamin E (Four Provinces Study). Atherosclerosis, 2010,212 : 543-547.
  • 9Kim JY, Kim OY, Paik JK, et al. Association of apolipoprotein A-V concentration with apolipoprotein A5 gene -1131T>C polymorphism and fasting triglyceride levels. J Clin Lipidol, 2013,7:94-101.
  • 10Sharma V, Forte TM, Ryan RO. Influence of apolipoprotein A-V on the metabolic fate of triacylglycerol. Curt Opin Lipidol,2013,24: 153-159.

二级参考文献52

  • 1李国平,王建跃,鄢盛恺,张立军,薛红,曾武威,吴刚,陈保生.人载脂蛋白A5基因多态性56C→G与血浆甘油三酯的关系[J].中国动脉硬化杂志,2004,12(5):574-576. 被引量：6
  • 2汤轶波,顾丽萍,孙屏,郭冬平,李晓宇,陈琪,范乐明.中国人内源性高甘油三酯血症与载脂蛋白A5基因-1131T>C多态性、S19W多态性的相关性[J].中国动脉硬化杂志,2005,13(6):785-788. 被引量：4
  • 3Hokanson JE, Austin MA. Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a meta- analysis of population-based prospective studies [ J ]. J Cardiovasc Risk, 1996,3 (2) : 213-219.
  • 4Pennacchio LA, Rubin EM. Genomic strategies to identify mammalian regulatory sequences [ J ]. Nat Rev Genet, 2001, 2(2) :100-109.
  • 5Van der Vliet HN, Sammels MG, Leegwater AC, et al. ApolipoproteinA-V : a novel apolipoprotein associated with an early phase of liver regeneration [J]. J Biol Chem, 2001, 276(48) :44512-44520.
  • 6Pennacchio LA, Rubin EM. Apolipoprotein A5, a newly identified gene that affects plasma triglyceride levels in humans and mice [ J ]. Arterioscler Thromb Vase Biol, 2003, 23 (4) :529-534.
  • 7Ong KL, Jiang CQ, Liu B, et al. Association of a genetic variant in the apolipoprotein A5 gene with the metabolic syndrome in Chinese [ J ]. Clin Endocrinol (Oxf), 2011,74(2):206-213.
  • 8Liu ZK, Hu M, Baum L, et al. Associations of polymorphisms in the apolipoprotein A1/C3/A4/A5 gene cluster with familial combined hyperlipidaemia in Hong Kong Chinese [ J]. Atherosclerosis, 2010, 208 (2) :427-432.
  • 9Webster RJ, Warrington NM, Weedon MN, et al. The association of common genetic variants in the APO AS, LPL and GCK genes with longitudinal changes in metabolic and cardiovascular traits [ J ]. Diabetologia, 2009, 52( 1 ) : 106-114.
  • 10Austin MA, Talmud PJ, Farin FM, et al. Association of apolipoprotein A5 variants with LDL particle size and triglyceride in Japanese Americans [ J ]. Biochim Biophys Acta, 2004, 1688( 1 ) : 1-9.

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实用检验医师杂志
2013年 第2期

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