60例心室颤动的临床分析

Clinical analysis of 60 cases of ventricular fibrillation

目的总结心室颤动(简称室颤)患者的临床特点,探讨可能影响室颤患者死亡的因素。方法对2006年1月至2011年3月在中山大学孙逸仙纪念医院住院并发生室颤患者的资料进行回顾性分析。结果入选室颤患者60例,年龄65.6±13.1岁,男女比例3.6∶1,冠心病占83.3%。60例室颤患者均发生晕厥,死亡38例(63.3%),仅3例植入埋藏式心脏转复除颤器(ICD)。生存组患者发生室颤到除颤的时间均在5min之内,明显小于死亡组。Logistic回归分析提示年龄和心力衰竭是室颤患者死亡的独立影响因素,OR值分别为4.3699和6.5218。结论室颤患者发病年龄大,男性多于女性,晕厥及死亡发生率高,及时电除颤是提高室颤患者生存率的重要因素。

Objective To summarize the clinical features of ventricular fibrillation （VF） and to explore the factors that may affect the mortality of VF. Methods We retrospectively reviewed the records of VF patients who were hospitalized in the Sun Yat-sen Memorial Hospital of Sun Yat-sen University between January 2006 and March 2011. Results There were 60 patients enrolled into the study with an average age of 65.6 ± 13.1 years old, male/female ratio was 3.6 ： 1. There were 83.3% of patients had coronary heart disease. All VF patients occurred syncope, and 38 （63.3%） of them die. On- ly 3 patients implanted implantable cardioverter defibrillator. The defibrillation time of patients in survival group was within 5 minutes, which was mach less than that in death group. Logistic regression analysis suggested age and heart failure were independent factors that influenced the death of VF patients, OR values were 4. 3699 and 6. 5218 respectively. Conclu- sions Patients with VF are usually old and men are more than women. The rate of syncope and sudden death are also high. Timely defibrillation is important factor to improve the survival rate of the VF.