70例脑卒中后癫痫的临床特点分析

Clinical characteristics of 70 patients of epilepsy after stroke

目的探讨脑卒中后癫痫的临床特点。方法选择该院收治的脑卒中后癫痫患者70例,对其癫痫发作的临床特点进行回顾性分析。结果该研究中脑卒中后癫痫的发生率,其中早发性癫痫的发生率(68.6%)显著高于迟发性癫痫(31.4%)(P<0.05);蛛网膜下腔出血癫痫部分性发作的占10.0%,显著低于脑梗死的53.8%和脑出血的52.4%(P<0.05);病灶位于皮层下的比例均明显低于病灶位于皮层的比例,大面积病灶的比例均明显高于小面积病灶的比例(P<0.05);脑卒中后癫痫组的焦虑、阻滞、认知障碍、全身症状、睡眠障碍、HAMD量表总分6项因子分均明显高于无癫痫组(P<0.05)。结论脑卒中后癫痫是脑卒中常见的并发症,以早发性癫痫为主,脑卒中类型、病灶部位、大小与卒中后癫痫发生相关。

Objective To investigate the epilepsy clinical characteristic from 70 patients after stroke. Methods 70 patients with epilep-sy after stroke were selected from the hospital＇s last 10 years＇ database, the clinical features of epilepsy were retrospectively analyzed. Results For the incidence of epilepsy after stroke in this study： The early expressed epilepsy （ 68.6% ） was significantly higher than late expressed epilepsy （31.4% ） （ P 〈 0. 05 ） ; In the 10 subarachnoid hemorrhage epliepsy patients, 10.0% of them had partial epilepsy, which significantly lower than cerebral infarction （ 53.8% ） and cerebral hemorrhage （ 52.4% ） （ P 〈 0.05 ） ; Subcortical stroke patients have less chances of epilepsy compared with cortex stroke patients, patients with larger stroke area have more chances of having epilepsy. （ P 〈 0. 05 ） ; Score for the anxiety, retardation, cognitive impairment, systemic symptoms, sleep disorders, HAMD in epilepsy after stroke group were significantly higher than stroke group（ P 〈 0.05 ）. Conclusions Epilepsy is a common complication after stroke. Most of the epilepsy will occur early. The type of the stroke, lesion location, lesion size will all have effect onto the expression of epilepsy.